The role of anaplastic lymphoma kinase in pediatric cancers
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چکیده
منابع مشابه
The role of anaplastic lymphoma kinase in pediatric cancers
The anaplastic lymphoma kinase (ALK) gene was initially identified as a fusion partner of the nucleophosmin gene in anaplastic large-cell lymphoma with t(2;5)(p23;q35) translocation, and then described with different genetic abnormalities in a number of tumors. Although ALK is known to be involved in the pathogenesis of neuroblastoma through activating mutations or gene amplification, its role ...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2017
ISSN: 1347-9032,1349-7006
DOI: 10.1111/cas.13333